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ALS Yeast Models—Past Success Stories and New Opportunities

In the past two decades, yeast models have delivered profound insights into basic mechanisms of protein misfolding and the dysfunction of key cellular pathways associated with amyotrophic lateral sclerosis (ALS). Expressing ALS-associated proteins, such as superoxide dismutase (SOD1), TAR DNA bindin...

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Detalles Bibliográficos
Autores principales: Di Gregorio, Sonja E., Duennwald, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218427/
https://www.ncbi.nlm.nih.gov/pubmed/30425620
http://dx.doi.org/10.3389/fnmol.2018.00394