Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

Aberrant expression of long noncoding RNA H19 has been associated with tumour progression, but the underlying molecular tumourigenesis mechanisms remain largely unknown. Here, we report that H19 expression is frequently downregulated in human primary pituitary adenomas and is negatively correlated w...

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Detalles Bibliográficos
Autores principales: Wu, Ze Rui, Yan, Lichong, Liu, Yan Ting, Cao, Lei, Guo, Yu Hang, Zhang, Yong, Yao, Hong, Cai, Lin, Shang, Han Bing, Rui, Wei Wei, Yang, Gang, Zhang, Xiao Biao, Tang, Hao, Wang, Yu, Huang, Jin Yan, Wei, Yong Xu, Zhao, Wei Guo, Su, Bing, Wu, Zhe Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218470/
https://www.ncbi.nlm.nih.gov/pubmed/30397197
http://dx.doi.org/10.1038/s41467-018-06853-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218470/
https://www.ncbi.nlm.nih.gov/pubmed/30397197
http://dx.doi.org/10.1038/s41467-018-06853-3

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