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Role of noise and parametric variation in the dynamics of gene regulatory circuits

Stochasticity in gene expression impacts the dynamics and functions of gene regulatory circuits. Intrinsic noises, including those that are caused by low copy number of molecules and transcriptional bursting, are usually studied by stochastic simulations. However, the role of extrinsic factors, such...

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Detalles Bibliográficos
Autores principales: Kohar, Vivek, Lu, Mingyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218471/
https://www.ncbi.nlm.nih.gov/pubmed/30416751
http://dx.doi.org/10.1038/s41540-018-0076-x