Cargando…

Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition

The interaction between natural killer (NK) cell inhibitory receptors and their cognate ligands constitutes a key mechanism by which healthy tissues are protected from NK cell-mediated lysis. However, self-ligand recognition remains poorly understood within the prototypical NKR-P1 receptor family. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Balaji, Gautham R., Aguilar, Oscar A., Tanaka, Miho, Shingu-Vazquez, Miguel A., Fu, Zhihui, Gully, Benjamin S., Lanier, Lewis L., Carlyle, James R., Rossjohn, Jamie, Berry, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218473/
https://www.ncbi.nlm.nih.gov/pubmed/30397201
http://dx.doi.org/10.1038/s41467-018-06989-2