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Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis
Many pro-inflammatory pathways leading to arthritis have global effects on the immune system rather than only acting locally in joints. The reason behind the regional and patchy distribution of arthritis represents a longstanding paradox. Here we show that biomechanical loading acts as a decisive fa...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218475/ https://www.ncbi.nlm.nih.gov/pubmed/30397205 http://dx.doi.org/10.1038/s41467-018-06933-4 |