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Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

The proteasomal system is responsible for the turnover of damaged proteins. Because of its important functions in oncogenesis, inhibiting the proteasomal system is a promising therapeutic approach for cancer treatment. Bortezomib (BTZ) is the first proteasome inhibitor approved by FDA for clinical a...

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Detalles Bibliográficos
Autores principales: Karademir, Betul, Sari, Gulce, Jannuzzi, Ayse Tarbin, Musunuri, Sravani, Wicher, Grzegorz, Grune, Tilman, Mi, Jia, Hacioglu-Bay, Husniye, Forsberg-Nilsson, Karin, Bergquist, Jonas, Jung, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218500/
https://www.ncbi.nlm.nih.gov/pubmed/30397214
http://dx.doi.org/10.1038/s41598-018-34507-3