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Step Sizes and Rate Constants of Single-headed Cytoplasmic Dynein Measured with Optical Tweezers

A power stroke of dynein is thought to be responsible for the stepping of dimeric dynein. However, the actual size of the displacement driven by a power stroke has not been directly measured. Here, the displacements of single-headed cytoplasmic dynein were measured by optical tweezers. The mean disp...

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Detalles Bibliográficos
Autores principales: Kinoshita, Yoshimi, Kambara, Taketoshi, Nishikawa, Kaori, Kaya, Motoshi, Higuchi, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218510/
https://www.ncbi.nlm.nih.gov/pubmed/30397249
http://dx.doi.org/10.1038/s41598-018-34549-7