Receptor-Ligand Interaction Mediates Targeting of Endothelial Colony Forming Cell-derived Exosomes to the Kidney after Ischemic Injury

Endothelial colony forming cell (ECFC)-derived exosomes protect mice against ischemic kidney injury, via transfer of microRNA-(miR)-486-5p. Mechanisms mediating exosome recruitment to tissues are unclear. We hypothesized that ECFC exosomes target ischemic kidneys, involving interaction between exoso...

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Detalles Bibliográficos
Autores principales: Viñas, Jose L., Spence, Matthew, Gutsol, Alex, Knoll, William, Burger, Dylan, Zimpelmann, Joseph, Allan, David S., Burns, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218514/
https://www.ncbi.nlm.nih.gov/pubmed/30397255
http://dx.doi.org/10.1038/s41598-018-34557-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218514/
https://www.ncbi.nlm.nih.gov/pubmed/30397255
http://dx.doi.org/10.1038/s41598-018-34557-7

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