Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype

The impact of anti-tuberculosis co-treatment on efavirenz (EFV) exposure is still uncertain as contradictory reports exist, and the relevance of CYP2B6*6 genetic polymorphism on efavirenz clearance while on-and-off anti-tuberculosis co-treatment is not well investigated. We investigated the determin...

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Detalles Bibliográficos
Autores principales: Kitabi, Eliford Ngaimisi, Minzi, Omary Mashiku Sylivester, Mugusi, Sabina, Sasi, Philip, Janabi, Mohamed, Mugusi, Ferdinand, Bertilsson, Leif, Burhenne, Jürgen, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218524/
https://www.ncbi.nlm.nih.gov/pubmed/30397233
http://dx.doi.org/10.1038/s41598-018-34674-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218524/
https://www.ncbi.nlm.nih.gov/pubmed/30397233
http://dx.doi.org/10.1038/s41598-018-34674-3

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