Cargando…

Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype

The impact of anti-tuberculosis co-treatment on efavirenz (EFV) exposure is still uncertain as contradictory reports exist, and the relevance of CYP2B6*6 genetic polymorphism on efavirenz clearance while on-and-off anti-tuberculosis co-treatment is not well investigated. We investigated the determin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kitabi, Eliford Ngaimisi, Minzi, Omary Mashiku Sylivester, Mugusi, Sabina, Sasi, Philip, Janabi, Mohamed, Mugusi, Ferdinand, Bertilsson, Leif, Burhenne, Jürgen, Aklillu, Eleni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218524/ https://www.ncbi.nlm.nih.gov/pubmed/30397233 http://dx.doi.org/10.1038/s41598-018-34674-3

Ejemplares similares

Neuropsychiatric manifestations among HIV-1 infected African patients receiving efavirenz-based cART with or without tuberculosis treatment containing rifampicin
por: Mugusi, Sabina, et al.
Publicado: (2018)

Importance of Ethnicity, CYP2B6 and ABCB1 Genotype for Efavirenz Pharmacokinetics and Treatment Outcomes: A Parallel-Group Prospective Cohort Study in Two Sub-Saharan Africa Populations
por: Ngaimisi, Eliford, et al.
Publicado: (2013)

Liver Enzyme Abnormalities and Associated Risk Factors in HIV Patients on Efavirenz-Based HAART with or without Tuberculosis Co-Infection in Tanzania
por: Mugusi, Sabina, et al.
Publicado: (2012)

Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania
por: Sungi, Selemani Saidi, et al.
Publicado: (2018)

Impact of Population and Pharmacogenetics Variations on Efavirenz Pharmacokinetics and Immunologic Outcomes During Anti-Tuberculosis Co-Therapy: A Parallel Prospective Cohort Study in Two Sub-Sahara African Populations
por: Mugusi, Sabina, et al.
Publicado: (2020)

Copy Number Variation of Fc Gamma Receptor Genes in HIV-Infected and HIV-Tuberculosis Co-Infected Individuals in Sub-Saharan Africa
por: Machado, Lee R., et al.
Publicado: (2013)

The influence of nevirapine and efavirenz-based anti-retroviral therapy on the pharmacokinetics of lumefantrine and anti-malarial dose recommendation in HIV-malaria co-treatment
por: Maganda, Betty A, et al.
Publicado: (2015)

Optimal single sampling time-point for monitoring of praziquantel exposure in children
por: Mnkugwe, Rajabu Hussein, et al.
Publicado: (2021)

CCL3L1 copy number, HIV load, and immune reconstitution in sub-Saharan Africans
por: Aklillu, Eleni, et al.
Publicado: (2013)

Predictors of Efavirenz Plasma Exposure, Auto-Induction Profile, and Effect of Pharmacogenetic Variations among HIV-Infected Children in Ethiopia: A Prospective Cohort Study
por: Chala, Adugna, et al.
Publicado: (2021)

Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of Schistosoma mansoni Infection
por: Minzi, Omary Mashiku, et al.
Publicado: (2021)

Genetic and non‐genetic factors influencing efavirenz population pharmacokinetics among human immunodeficiency virus‐1‐infected children in Ethiopia
por: Chala, Adugna, et al.
Publicado: (2023)

Comparison of bioavailability between the most available generic tablet formulation containing artemether and lumefantrine on the Tanzanian market and the innovator’s product
por: Minzi, Omary MS, et al.
Publicado: (2013)

Risk Factors for Alanine Aminotransferase Elevations in a Prospective Cohort of HIV-Infected Tanzanian Adults Initiating Antiretroviral Therapy
por: Mugusi, Sabina F., et al.
Publicado: (2019)

Vitamin D and HIV Progression among Tanzanian Adults Initiating Antiretroviral Therapy
por: Sudfeld, Christopher R., et al.
Publicado: (2012)

Comparison of malaria treatment outcome of generic and innovator’s anti-malarial drugs containing artemether–lumefantrine combination in the management of uncomplicated malaria amongst Tanzanian children
por: Kilonzi, Manase, et al.
Publicado: (2019)

Effect of aspirin on HIV disease progression among HIV-infected individuals initiating antiretroviral therapy: study protocol for a randomised controlled trial
por: Mwakyandile, Tosi, et al.
Publicado: (2021)

Adherence to artemether-lumefantrine drug combination: a rural community experience six years after change of malaria treatment policy in Tanzania
por: Minzi, Omary, et al.
Publicado: (2014)

Adherence to artemether-lumefantrine drug combination: a rural community experience six years after change of malaria treatment policy in Tanzania
por: Minzi, Omary, et al.
Publicado: (2014)

Adherence to combination antiretroviral therapy among orphaned children in Dar es Salaam, Tanzania
por: Mugusi, Sabina F., et al.
Publicado: (2019)

HIV/AIDS Clinical Manifestations and their Implication for Patient Clinical Staging in Resource Limited Settings in Tanzania
por: Boniphace, Idindili, et al.
Publicado: (2011)

Self-initiation of antiretroviral therapy in the developing world: the involvement of private pharmacies in an HIV program
por: Minzi, Omary Mashiku, et al.
Publicado: (2012)

Prevalence and risk factors for efavirenz-based antiretroviral treatment–associated severe vitamin D deficiency: A prospective cohort study
por: Nylén, Hanna, et al.
Publicado: (2016)

Early or deferred initiation of efavirenz during rifampicin‐based TB therapy has no significant effect on CYP3A induction in TB‐HIV infected patients
por: Aklillu, Eleni, et al.
Publicado: (2020)

Enumeration of CD4(+) T-Cells Using a Portable Microchip Count Platform in Tanzanian HIV-Infected Patients
por: Moon, SangJun, et al.
Publicado: (2011)

CYP3A and CYP2B6 Genotype Predicts Glucose Metabolism Disorder among HIV Patients on Long-Term Efavirenz-Based ART: A Case-Control Study
por: Tadesse, Wondmagegn Tamiru, et al.
Publicado: (2022)

Impact of CYP2B6 and CYP2A6 polymorphisms on efavirenz plasma concentrations in Ghanaian HIV-infected patients
por: Zhang, Y, et al.
Publicado: (2010)

Efficacy of vitamin D(3) supplementation in reducing incidence of pulmonary tuberculosis and mortality among HIV-infected Tanzanian adults initiating antiretroviral therapy: study protocol for a randomized controlled trial
por: Sudfeld, Christopher R., et al.
Publicado: (2017)

Drug resistance testing through remote genotyping and predicted treatment options in human immunodeficiency virus type 1 infected Tanzanian subjects failing first or second line antiretroviral therapy
por: Svärd, Jenny, et al.
Publicado: (2017)

Inhaler Non-Adherence, Associated Factors and Asthma Control among Asthma Patients in a Tertiary Level Hospital in Tanzania
por: Shayo, Grace A., et al.
Publicado: (2022)

Constitutive androstane receptor and pregnane X receptor genotype influence efavirenz plasma concentration and CYP2B6 enzyme activity
por: Petros, Zelalem, et al.
Publicado: (2022)

Case‐fatality and disability in the Tanzanian Stroke Incidence Project cohort
por: Walker, R. W., et al.
Publicado: (2015)

Effect of CYP2B6 Gene Polymorphisms on Efavirenz Plasma Concentrations in Chinese Patients with HIV Infection
por: Meng, Xianmin, et al.
Publicado: (2015)

Dose Optimization of Efavirenz Based on Individual CYP2B6 Polymorphisms in Chinese Patients Positive for HIV
por: Hui, KH, et al.
Publicado: (2016)

Pharmacogenetic-Based Efavirenz Dose Modification: Suggestions for an African Population and the Different CYP2B6 Genotypes
por: Mukonzo, Jackson K., et al.
Publicado: (2014)

AIDS and HIV Infection after Thirty Years
por: Ippolito, Giuseppe, et al.
Publicado: (2013)

Safety and Tolerability of Ivermectin and Albendazole Mass Drug Administration in Lymphatic Filariasis Endemic Communities of Tanzania: A Cohort Event Monitoring Study
por: Fimbo, Adam M., et al.
Publicado: (2022)

The prevalence and pattern of antibiotic prescription among insured patients in Dar es Salaam Tanzania
por: Khalfan, Mohamed Ally, et al.
Publicado: (2021)

Species distribution and in vitro antifungal susceptibility of oral yeast isolates from Tanzanian HIV-infected patients with primary and recurrent oropharyngeal candidiasis
por: Hamza, Omar JM, et al.
Publicado: (2008)

Genetic variants in CYP2B6 and CYP2A6 explain interindividual variation in efavirenz plasma concentrations of HIV-infected children with diverse ethnic origin
por: Soeria-Atmadja, Sandra, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pr1scv7lbnfgsohoo31eg8folc