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Machine Learning Reveals Protein Signatures in CSF and Plasma Fluids of Clinical Value for ALS

We use shotgun proteomics to identify biomarkers of diagnostic and prognostic value in individuals diagnosed with amyotrophic lateral sclerosis. Matched cerebrospinal and plasma fluids were subjected to abundant protein depletion and analyzed by nano-flow liquid chromatography high resolution tandem...

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Detalles Bibliográficos
Autores principales: Bereman, Michael S., Beri, Joshua, Enders, Jeffrey R., Nash, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218542/
https://www.ncbi.nlm.nih.gov/pubmed/30397248
http://dx.doi.org/10.1038/s41598-018-34642-x