Cargando…

Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes

T-box (TBX) transcription factors are evolutionary conserved genes and master transcriptional regulators. In mammals, TBX2 subfamily (TBX2, TBX3, TBX4, and TBX5) genes are expressed in the developing lung bud and tracheae. Our group previously showed that the expression of TBX2 subfamily was signifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Khalil, Athar, Dekmak, Batoul, Boulos, Fouad, Kantrowitz, Jake, Spira, Avrum, Fujimoto, Junya, Kadara, Humam, El-Hachem, Nehme, Nemer, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218583/
https://www.ncbi.nlm.nih.gov/pubmed/30425966
http://dx.doi.org/10.3389/fonc.2018.00482