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Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE

Monoclonal antibodies and derived fragments are used extensively both experimentally and therapeutically. Thorough characterization of such antibodies is necessary and includes assessment of their thermal and storage stabilities. Thus, assessment of the underlying conformational stabilities of the a...

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Detalles Bibliográficos
Autores principales: Kirley, Terence L., Greis, Kenneth D., Norman, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218646/
https://www.ncbi.nlm.nih.gov/pubmed/30417132
http://dx.doi.org/10.1016/j.bbrep.2018.10.004