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Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE
Monoclonal antibodies and derived fragments are used extensively both experimentally and therapeutically. Thorough characterization of such antibodies is necessary and includes assessment of their thermal and storage stabilities. Thus, assessment of the underlying conformational stabilities of the a...
Autores principales: | Kirley, Terence L., Greis, Kenneth D., Norman, Andrew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218646/ https://www.ncbi.nlm.nih.gov/pubmed/30417132 http://dx.doi.org/10.1016/j.bbrep.2018.10.004 |
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