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Repurposing Proteostasis-Modifying Drugs to Prevent or Treat Age-Related Dementia: A Systematic Review

Background: Dementia has a significant impact on quality of life of older individuals. Impaired proteostasis has been implicated as a potential cause of dementia, that can be therapeutically targeted to improve patient outcomes. This review aimed to collate all current evidence of the potential for...

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Detalles Bibliográficos
Autores principales: Heard, Daniel S., Tuttle, Camilla S. L., Lautenschlager, Nicola T., Maier, Andrea B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218672/
https://www.ncbi.nlm.nih.gov/pubmed/30425653
http://dx.doi.org/10.3389/fphys.2018.01520