Balanced Activity between Kv3 and Nav Channels Determines Fast-Spiking in Mammalian Central Neurons

Fast-spiking (FS) neurons can fire action potentials (APs) up to 1,000 Hz and play key roles in vital functions such as sound location, motor coordination, and cognition. Here we report that the concerted actions of Kv3 voltage-gated K(+) (Kv) and Na(+) (Nav) channels are sufficient and necessary fo...

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Detalles Bibliográficos
Autores principales: Gu, Yuanzheng, Servello, Dustin, Han, Zhi, Lalchandani, Rupa R., Ding, Jun B., Huang, Kun, Gu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218699/
https://www.ncbi.nlm.nih.gov/pubmed/30390433
http://dx.doi.org/10.1016/j.isci.2018.10.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218699/
https://www.ncbi.nlm.nih.gov/pubmed/30390433
http://dx.doi.org/10.1016/j.isci.2018.10.014

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