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Balanced Activity between Kv3 and Nav Channels Determines Fast-Spiking in Mammalian Central Neurons
Fast-spiking (FS) neurons can fire action potentials (APs) up to 1,000 Hz and play key roles in vital functions such as sound location, motor coordination, and cognition. Here we report that the concerted actions of Kv3 voltage-gated K(+) (Kv) and Na(+) (Nav) channels are sufficient and necessary fo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218699/ https://www.ncbi.nlm.nih.gov/pubmed/30390433 http://dx.doi.org/10.1016/j.isci.2018.10.014 |