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Biological consequences of structural and functional proteasome diversity

Cell homeostasis and regulation of metabolic pathways are ensured by synthesis, proper folding and efficient degradation of a vast amount of proteins. Ubiquitin-proteasome system (UPS) degrades most intracellular proteins and thus, participates in regulation of cellular metabolism. Within the UPS, p...

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Detalles Bibliográficos
Autores principales: Morozov, Alexey V., Karpov, Vadim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218844/
https://www.ncbi.nlm.nih.gov/pubmed/30417153
http://dx.doi.org/10.1016/j.heliyon.2018.e00894