Cargando…
PA28αβ overexpression enhances learning and memory of female mice without inducing 20S proteasome activity
BACKGROUND: The proteasome system plays an important role in synaptic plasticity. Induction and maintenance of long term potentiation is directly dependent on selective targeting of proteins for proteasomal degradation. The 20S proteasome activator PA28αβ activates hydrolysis of small nonubiquitinat...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218978/ https://www.ncbi.nlm.nih.gov/pubmed/30400847 http://dx.doi.org/10.1186/s12868-018-0468-2 |