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Single sample scoring of molecular phenotypes

BACKGROUND: Gene set scoring provides a useful approach for quantifying concordance between sample transcriptomes and selected molecular signatures. Most methods use information from all samples to score an individual sample, leading to unstable scores in small data sets and introducing biases from...

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Detalles Bibliográficos
Autores principales: Foroutan, Momeneh, Bhuva, Dharmesh D., Lyu, Ruqian, Horan, Kristy, Cursons, Joseph, Davis, Melissa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219008/
https://www.ncbi.nlm.nih.gov/pubmed/30400809
http://dx.doi.org/10.1186/s12859-018-2435-4