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New guidance to improve sample size calculations for trials: eliciting the target difference

BACKGROUND: Sample size calculations are central to the design of health research trials. To ensure that the trial provides good evidence to answer the trial’s research question, the target effect size (difference in means or proportions, odds ratio, relative risk or hazard ratio between trial arms)...

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Detalles Bibliográficos
Autor principal: Bell, Melanie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219024/
https://www.ncbi.nlm.nih.gov/pubmed/30396364
http://dx.doi.org/10.1186/s13063-018-2894-y