Porcine reproductive and respiratory syndrome virus inhibits MARC-145 proliferation via inducing apoptosis and G2/M arrest by activation of Chk/Cdc25C and p53/p21 pathway

Porcine reproductive and respiratory syndrome virus(PRRSV) is an important immunosuppressive virus which can suppresses infected cells proliferation. In this work, we examined PRRSV ability to manipulate cell cycle progression of MARC-145 cells and explored the potential molecular mechanisms. The re...

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Detalles Bibliográficos
Autores principales: Song, Linlin, Han, Ximeng, Jia, Cunyu, Zhang, Xin, Jiao, Yunjie, Du, Taofeng, Xiao, Shuqi, Hiscox, Julian A., Zhou, En-Min, Mu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219034/
https://www.ncbi.nlm.nih.gov/pubmed/30400903
http://dx.doi.org/10.1186/s12985-018-1081-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219034/
https://www.ncbi.nlm.nih.gov/pubmed/30400903
http://dx.doi.org/10.1186/s12985-018-1081-9

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