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Glioma cell proliferation is enhanced in the presence of tumor-derived cilia vesicles

BACKGROUND: The mechanisms by which primary cilia affect glioma pathogenesis are unclear. Depending on the glioma cell line, primary cilia can promote or inhibit tumor development. Here, we used piggyBac-mediated transgenesis to generate patient-derived glioblastoma (GBM) cell lines that stably expr...

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Detalles Bibliográficos
Autores principales: Hoang-Minh, Lan B., Dutra-Clarke, Marina, Breunig, Joshua J., Sarkisian, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219037/
https://www.ncbi.nlm.nih.gov/pubmed/30410731
http://dx.doi.org/10.1186/s13630-018-0060-5