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CRISPR/Cas9 offers a new tool for studying the role of chromatin architecture in disease pathogenesis
A recent study used CRISPR/Cas9 to reveal long-range looping between disease-related genes and their regulatory elements that is mediated by the CCCTC-binding factor (CTCF) in prostate cancer.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219166/ https://www.ncbi.nlm.nih.gov/pubmed/30400943 http://dx.doi.org/10.1186/s13059-018-1569-z |