Cargando…

Transposase mapping identifies the genomic targets of BAP1 in uveal melanoma

BACKGROUND: BAP1 is a histone deubiquitinase that acts as a tumor and metastasis suppressor associated with disease progression in human cancer. We have used the “Calling Card System” of transposase-directed transposon insertion mapping to identify the genomic targets of BAP1 in uveal melanoma (UM)....

Descripción completa

Detalles Bibliográficos
Autores principales: Yen, Matthew, Qi, Zongtai, Chen, Xuhua, Cooper, John A., Mitra, Robi D., Onken, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219186/
https://www.ncbi.nlm.nih.gov/pubmed/30400891
http://dx.doi.org/10.1186/s12920-018-0424-0