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Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP

BACKGROUND: Among human T cell leukemia virus type 1 (HTLV-1)-infected individuals, there is an association between HTLV-1 tax subgroups (subgroup-A or subgroup-B) and the risk of HAM/TSP in the Japanese population. To investigate the role of HTLV-1 subgroups in viral pathogenesis, we studied the fu...

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Detalles Bibliográficos
Autores principales: Naito, Tadasuke, Yasunaga, Jun-ichirou, Mitobe, Yuichi, Shirai, Kazumasa, Sejima, Hiroe, Ushirogawa, Hiroshi, Tanaka, Yuetsu, Nakamura, Tatsufumi, Hanada, Kousuke, Fujii, Masahiro, Matsuoka, Masao, Saito, Mineki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219256/
https://www.ncbi.nlm.nih.gov/pubmed/30400920
http://dx.doi.org/10.1186/s12977-018-0454-x