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MicroRNA-31-5p regulates chemosensitivity by preventing the nuclear location of PARP1 in hepatocellular carcinoma

BACKGROUND: MicroRNAs (miRNAs) posttranscriptionally regulate gene expression and thereby contribute to the modulation of numerous complex and disease-relevant cellular processes, including cell proliferation, cell motility, apoptosis and stress response. miRNA-31-5p is encoded on a genomic fragile...

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Detalles Bibliográficos
Autores principales: Que, Ke-ting, Zhou, Yun, You, Yu, Zhang, Zhen, Zhao, Xiao-ping, Gong, Jian-ping, Liu, Zuo-jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219257/
https://www.ncbi.nlm.nih.gov/pubmed/30400960
http://dx.doi.org/10.1186/s13046-018-0930-0