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Novel mechanism responsible for high-level macrolide resistance in Moraxella catarrhalis

BACKGROUND: High-level macrolide-resistant Moraxella catarrhalis strains have been isolated; however, the underlying mechanism has not been well elucidated. We investigated the role of mutations in the 23S rRNA gene and the L4 and L22 ribosomal proteins using spontaneous erythromycin-resistant mutan...

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Detalles Bibliográficos
Autores principales: Kasai, Ayako, Ohta, Ayaka, Maeda, Yuina, Yamada, Kageto, Tao, Kazuyuki, Saito, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219419/
https://www.ncbi.nlm.nih.gov/pubmed/30464556
http://dx.doi.org/10.2147/IDR.S181714