Activation of spinal nociceptin receptors induces cardiovascular depression and antinociception in an independent manner in mice

PURPOSE: The nociceptin receptor (NOP) was discovered in 1994 and was designated opioid-like receptor; activation of NOP leads to reduced neuronal excitability. Although suggested by the anatomical localization of NOP in brain or spinal cord, the cardiovascular or nociceptive effects of its endogeno...

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Detalles Bibliográficos
Autores principales: Tsai, Ching-Yi, Poon, Yan-Yuen, Huang, Ya-Hui, Chan, Samuel HH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219425/
https://www.ncbi.nlm.nih.gov/pubmed/30464587
http://dx.doi.org/10.2147/JPR.S175259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219425/
https://www.ncbi.nlm.nih.gov/pubmed/30464587
http://dx.doi.org/10.2147/JPR.S175259

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