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Activation of spinal nociceptin receptors induces cardiovascular depression and antinociception in an independent manner in mice
PURPOSE: The nociceptin receptor (NOP) was discovered in 1994 and was designated opioid-like receptor; activation of NOP leads to reduced neuronal excitability. Although suggested by the anatomical localization of NOP in brain or spinal cord, the cardiovascular or nociceptive effects of its endogeno...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219425/ https://www.ncbi.nlm.nih.gov/pubmed/30464587 http://dx.doi.org/10.2147/JPR.S175259 |