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Nuclear transport inhibition in acute myeloid leukemia: recent advances and future perspectives
Selective inhibitors of nuclear export (SINE) are emerging as a potentially efficacious therapeutic strategy for overcoming resistance to conventional chemotherapy for acute myeloid leukemia. SINE specifically block the protein Exportin 1, also known as chromosomal region maintenance 1, leading to n...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Future Medicine Ltd
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219429/ https://www.ncbi.nlm.nih.gov/pubmed/30405902 http://dx.doi.org/10.2217/ijh-2018-0001 |