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Mutational spectra and mutational signatures: Insights into cancer aetiology and mechanisms of DNA damage and repair
Reporter gene assays, in which a single mutation from each experiment can contribute to the assembly of a mutation spectrum for an agent, have provided the basis for understanding the mutational processes induced by mutagenic agents and for providing clues to the origins of mutations in human tumour...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219445/ https://www.ncbi.nlm.nih.gov/pubmed/30236628 http://dx.doi.org/10.1016/j.dnarep.2018.08.003 |