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Preserving replication fork integrity and competence via the homologous recombination pathway

Flaws in the DNA replication process have emerged as a leading driver of genome instability in human diseases. Alteration to replication fork progression is a defining feature of replication stress and the consequent failure to maintain fork integrity and complete genome duplication within a single...

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Detalles Bibliográficos
Autores principales: Ait Saada, Anissia, Lambert, Sarah A.E., Carr, Antony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219450/
https://www.ncbi.nlm.nih.gov/pubmed/30220600
http://dx.doi.org/10.1016/j.dnarep.2018.08.017