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Preserving replication fork integrity and competence via the homologous recombination pathway
Flaws in the DNA replication process have emerged as a leading driver of genome instability in human diseases. Alteration to replication fork progression is a defining feature of replication stress and the consequent failure to maintain fork integrity and complete genome duplication within a single...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219450/ https://www.ncbi.nlm.nih.gov/pubmed/30220600 http://dx.doi.org/10.1016/j.dnarep.2018.08.017 |