DNA protein crosslink proteolysis repair: From yeast to premature ageing and cancer in humans

DNA-protein crosslinks (DPCs) are a specific type of DNA lesion consisting of a protein covalently and irreversibly bound to DNA, which arise after exposure to physical and chemical crosslinking agents. DPCs can be bulky and thereby pose a barrier to DNA replication and transcription. The persistenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Fielden, John, Ruggiano, Annamaria, Popović, Marta, Ramadan, Kristijan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219452/
https://www.ncbi.nlm.nih.gov/pubmed/30170832
http://dx.doi.org/10.1016/j.dnarep.2018.08.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219452/
https://www.ncbi.nlm.nih.gov/pubmed/30170832
http://dx.doi.org/10.1016/j.dnarep.2018.08.025

Ejemplares similares