An inactivated poliovirus vaccine using Sabin strains produced on the serum-free PER.C6® cell culture platform is immunogenic and safe in a non-human primate model

BACKGROUND: The World Health Organization recommends the development of affordable next-generation inactivated poliovirus vaccines (IPV) using attenuated poliovirus Sabin strains. Previously, we introduced a novel PER.C6® cell culture platform, which allows for high yield production of an affordable...

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Detalles Bibliográficos
Autores principales: Bockstal, Viki, Tiemessen, Machteld M., Achterberg, Rogier, Van Wordragen, Carlo, Knaapen, Ad M., Serroyen, Jan, Marissen, Wilfred E., Schuitemaker, Hanneke, Zahn, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219454/
https://www.ncbi.nlm.nih.gov/pubmed/30314910
http://dx.doi.org/10.1016/j.vaccine.2018.09.068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219454/
https://www.ncbi.nlm.nih.gov/pubmed/30314910
http://dx.doi.org/10.1016/j.vaccine.2018.09.068

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