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GATA4 as a novel regulator involved in the development of the neural crest and craniofacial skeleton via Barx1

The role of GATA-binding protein 4 (GATA4) in neural crest cells (NCCs) is poorly defined. Here we showed that mouse NCCs lacking GATA4 exhibited developmental defects in craniofacial bone, teeth, and heart. The defects likely occurred due to decreased cell proliferation at the developmental stage....

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Detalles Bibliográficos
Autores principales: Guo, Shuyu, Zhang, Yuxin, Zhou, Tingting, Wang, Dongyue, Weng, Yajuan, Chen, Qi, Ma, Junqing, Li, Yi-ping, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219484/
https://www.ncbi.nlm.nih.gov/pubmed/29523871
http://dx.doi.org/10.1038/s41418-018-0083-x