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GATA4 as a novel regulator involved in the development of the neural crest and craniofacial skeleton via Barx1
The role of GATA-binding protein 4 (GATA4) in neural crest cells (NCCs) is poorly defined. Here we showed that mouse NCCs lacking GATA4 exhibited developmental defects in craniofacial bone, teeth, and heart. The defects likely occurred due to decreased cell proliferation at the developmental stage....
Autores principales: | Guo, Shuyu, Zhang, Yuxin, Zhou, Tingting, Wang, Dongyue, Weng, Yajuan, Chen, Qi, Ma, Junqing, Li, Yi-ping, Wang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219484/ https://www.ncbi.nlm.nih.gov/pubmed/29523871 http://dx.doi.org/10.1038/s41418-018-0083-x |
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