Profilin-1 deficiency leads to SMAD3 upregulation and impaired 3D outgrowth of breast cancer cells

BACKGROUND: Adhesion-mediated activation of FAK/ERK signalling pathway, enabled by the formation of filopodial protrusions (FLP), has been shown to be an important event for triggering of dormancy-to-proliferation switch and metastatic outgrowth of breast cancer cells (BCC). We studied the role of a...

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Detalles Bibliográficos
Autores principales: Chakraborty, Souvik, Jiang, Chang, Gau, David, Oddo, Michael, Ding, Zhijie, Vollmer, Laura, Joy, Marion, Schiemann, William, Stolz, Donna Beer, Vogt, Andreas, Ghosh, Sujoy, Roy, Partha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219497/
https://www.ncbi.nlm.nih.gov/pubmed/30318519
http://dx.doi.org/10.1038/s41416-018-0284-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219497/
https://www.ncbi.nlm.nih.gov/pubmed/30318519
http://dx.doi.org/10.1038/s41416-018-0284-6

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