Long-term efficacy, tolerability and overall survival in patients with platinum-sensitive, recurrent high-grade serous ovarian cancer treated with maintenance olaparib capsules following response to chemotherapy

BACKGROUND: In Study 19, maintenance monotherapy with olaparib significantly prolonged progression-free survival vs placebo in patients with platinum-sensitive, recurrent high-grade serous ovarian cancer. METHODS: Study 19 was a randomised, placebo-controlled, Phase II trial enrolling 265 patients w...

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Detalles Bibliográficos
Autores principales: Friedlander, Michael, Matulonis, Ursula, Gourley, Charlie, du Bois, Andreas, Vergote, Ignace, Rustin, Gordon, Scott, Clare, Meier, Werner, Shapira-Frommer, Ronnie, Safra, Tamar, Matei, Daniela, Shirinkin, Vadim, Selle, Frédéric, Fielding, Anitra, Lowe, Elizabeth S., McMurtry, Emma L., Spencer, Stuart, Rowe, Philip, Mann, Helen, Parry, David, Ledermann, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219499/
https://www.ncbi.nlm.nih.gov/pubmed/30353045
http://dx.doi.org/10.1038/s41416-018-0271-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219499/
https://www.ncbi.nlm.nih.gov/pubmed/30353045
http://dx.doi.org/10.1038/s41416-018-0271-y

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