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Phenotype-independent DNA methylation changes in prostate cancer

BACKGROUND: Human prostate cancers display numerous DNA methylation changes compared to normal tissue samples. However, definitive identification of features related to the cells’ malignant status has been compromised by the predominance of cells with luminal features in prostate cancers. METHODS: W...

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Detalles Bibliográficos
Autores principales: Pellacani, Davide, Droop, Alastair P., Frame, Fiona M., Simms, Matthew S., Mann, Vincent M., Collins, Anne T., Eaves, Connie J., Maitland, Norman J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219500/
https://www.ncbi.nlm.nih.gov/pubmed/30318509
http://dx.doi.org/10.1038/s41416-018-0236-1