High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes

Nucleosomes play a dual role in compacting the genome and regulating the access to DNA. To unravel the underlying mechanism, we study fluorescently labeled mononucleosomes by multi-parameter FRET measurements and characterize their structural and dynamic heterogeneity upon NaCl-induced destabilizati...

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Detalles Bibliográficos
Autores principales: Gansen, Alexander, Felekyan, Suren, Kühnemuth, Ralf, Lehmann, Kathrin, Tóth, Katalin, Seidel, Claus A. M., Langowski, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219519/
https://www.ncbi.nlm.nih.gov/pubmed/30401903
http://dx.doi.org/10.1038/s41467-018-06758-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219519/
https://www.ncbi.nlm.nih.gov/pubmed/30401903
http://dx.doi.org/10.1038/s41467-018-06758-1

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