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High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes
Nucleosomes play a dual role in compacting the genome and regulating the access to DNA. To unravel the underlying mechanism, we study fluorescently labeled mononucleosomes by multi-parameter FRET measurements and characterize their structural and dynamic heterogeneity upon NaCl-induced destabilizati...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219519/ https://www.ncbi.nlm.nih.gov/pubmed/30401903 http://dx.doi.org/10.1038/s41467-018-06758-1 |