β-Glucuronidases of opportunistic bacteria are the major contributors to xenobiotic-induced toxicity in the gut

Gut bacterial β-D-glucuronidases (GUSs) catalyze the removal of glucuronic acid from liver-produced β-D-glucuronides. These reactions can have deleterious consequences when they reverse xenobiotic metabolism. The human gut contains hundreds of GUSs of variable sequences and structures. To understand...

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Detalles Bibliográficos
Autores principales: Dashnyam, Punsaldulam, Mudududdla, Ramesh, Hsieh, Tung-Ju, Lin, Ting-Chien, Lin, Hsien-Ya, Chen, Peng-Yuan, Hsu, Chia-Yi, Lin, Chun-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219552/
https://www.ncbi.nlm.nih.gov/pubmed/30401818
http://dx.doi.org/10.1038/s41598-018-34678-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219552/
https://www.ncbi.nlm.nih.gov/pubmed/30401818
http://dx.doi.org/10.1038/s41598-018-34678-z

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