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An Electroencephalography Bioassay for Preclinical Testing of Analgesic Efficacy

We present a multimodal method combining quantitative electroencephalography (EEG), behavior and pharmacology for pre-clinical screening of analgesic efficacy in vivo. The method consists of an objective and non-invasive approach for realtime assessment of spontaneous nociceptive states based on EEG...

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Detalles Bibliográficos
Autores principales: Koyama, Suguru, LeBlanc, Brian W., Smith, Kelsey A., Roach, Catherine, Levitt, Joshua, Edhi, Muhammad M., Michishita, Mai, Komatsu, Takayuki, Mashita, Okishi, Tanikawa, Aki, Yoshikawa, Satoru, Saab, Carl Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219560/
https://www.ncbi.nlm.nih.gov/pubmed/30401974
http://dx.doi.org/10.1038/s41598-018-34594-2