Touchscreen testing reveals clinically relevant cognitive abnormalities in a mouse model of schizophrenia lacking metabotropic glutamate receptor 5

Metabotropic glutamate receptor 5 (mGlu5) has been implicated in certain forms of synaptic plasticity and cognitive function. mGlu5 knockout (KO) mice and mGlu5 antagonists have been previously used to study the pathophysiology of schizophrenia as they have been shown respectively to display or indu...

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Detalles Bibliográficos
Autores principales: Zeleznikow-Johnston, Ariel M., Renoir, Thibault, Churilov, Leonid, Li, Shanshan, Burrows, Emma L., Hannan, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219561/
https://www.ncbi.nlm.nih.gov/pubmed/30401923
http://dx.doi.org/10.1038/s41598-018-33929-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219561/
https://www.ncbi.nlm.nih.gov/pubmed/30401923
http://dx.doi.org/10.1038/s41598-018-33929-3

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