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Immortalized murine fibroblast cell lines are refractory to reprogramming to pluripotent state

To date different cell types of various mammalian species have been reprogrammed to induced pluripotent stem cells (iPSCs) using Yamanaka's cocktail of transcription factors (Oct4, Klf4, Sox2, and cMyc). It has been shown that several primary human cancer cell lines could be reprogrammed to iPS...

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Detalles Bibliográficos
Autores principales: Skvortsova, Elena V., Sinenko, Sergey A., Tomilin, Alexey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219659/
https://www.ncbi.nlm.nih.gov/pubmed/30443291
http://dx.doi.org/10.18632/oncotarget.26235