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Aneuploidy in intestinal stem cells promotes gut dysplasia in Drosophila

Aneuploidy is associated with different human diseases including cancer. However, different cell types appear to respond differently to aneuploidy, either by promoting tumorigenesis or causing cell death. We set out to study the behavior of adult Drosophila melanogaster intestinal stem cells (ISCs)...

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Detalles Bibliográficos
Autores principales: Resende, Luís Pedro, Monteiro, Augusta, Brás, Rita, Lopes, Tatiana, Sunkel, Claudio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219720/
https://www.ncbi.nlm.nih.gov/pubmed/30282810
http://dx.doi.org/10.1083/jcb.201804205