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Talin as a mechanosensitive signaling hub

Cell adhesion to the extracellular matrix (ECM), mediated by transmembrane receptors of the integrin family, is exquisitely sensitive to biochemical, structural, and mechanical features of the ECM. Talin is a cytoplasmic protein consisting of a globular head domain and a series of α-helical bundles...

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Detalles Bibliográficos
Autores principales: Goult, Benjamin T., Yan, Jie, Schwartz, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219721/
https://www.ncbi.nlm.nih.gov/pubmed/30254032
http://dx.doi.org/10.1083/jcb.201808061