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Oligomerization of the FERM-FA protein Yurt controls epithelial cell polarity

Drosophila melanogaster Yurt (Yrt) and its mammalian orthologue EPB41L5 limit apical membrane growth in polarized epithelia. EPB41L5 also supports epithelial–mesenchymal transition and metastasis. Yrt and EPB41L5 contain a four-point-one, ezrin, radixin, and moesin (FERM) domain and a FERM-adjacent...

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Detalles Bibliográficos
Autores principales: Gamblin, Clémence L., Parent-Prévost, Frédérique, Jacquet, Kévin, Biehler, Cornélia, Jetté, Alexandra, Laprise, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219725/
https://www.ncbi.nlm.nih.gov/pubmed/30082297
http://dx.doi.org/10.1083/jcb.201803099