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Oligomerization of the FERM-FA protein Yurt controls epithelial cell polarity
Drosophila melanogaster Yurt (Yrt) and its mammalian orthologue EPB41L5 limit apical membrane growth in polarized epithelia. EPB41L5 also supports epithelial–mesenchymal transition and metastasis. Yrt and EPB41L5 contain a four-point-one, ezrin, radixin, and moesin (FERM) domain and a FERM-adjacent...
Autores principales: | Gamblin, Clémence L., Parent-Prévost, Frédérique, Jacquet, Kévin, Biehler, Cornélia, Jetté, Alexandra, Laprise, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219725/ https://www.ncbi.nlm.nih.gov/pubmed/30082297 http://dx.doi.org/10.1083/jcb.201803099 |
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